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chronic pulmonary aspergillosis (cpa) and aspergilloma | aspergillus & aspergillosis website skip to main content aspergillus & aspergillosis website living with it working with it treating it search form search main menu home about us site map with rss feeds survey privacy policy terms & conditions website sponsors register/login what's new jobs latest additions news blog newsletters news for the press patients drug interactions map of people with aspergillosis nac support meetings official public launch national aspergillosis centre patients website q and a support group spore report uk supplements and herbs support communities (eg facebook) scientific air quality aspergillus proteins biodeterioration conferences/courses & events calendar genomes geo-microbiology lab protocols mycology courses mycotoxins/metabolites q & a support group for professionals societies & groups species database strain database prehistoric fungi medical treatment of aspergillosis and aspergilloma antifungal drugs spc diagnosis of aspergillus infection drug interactions pro antifungal stewardship paediatric fungal infections case histories new drugs for aspergillosis clinical trials aspergillosis clinicaltrials.gov nhs choices who database antifungal clinicaltrials.gov nhs choices who database jobs veterinary information other fungal infection (life-worldwide) marijuana use and aspergillosis global aspergillosis statistics england aspergillosis statistics library advances against aspergillosis article database books open access conference abstracts conferences/courses & events calendar history of aspergillus & obituaries mycological and medical mycological societies milestones of aspergillosis & fungal disease newspaper cuttings theses resources education education and teaching tools cpd/cme information leaflets slide presentations website slide collection imported slides powershow - aspergillosis powershow - aspergillus medical & patient videos molecular mycology e-course images & video images library videos specific patients video clips (cell biology) flickr images aspergillus art competition for schoolchildren aspergillus art competition for schoolchildren - finalists artwork by aspergillosis patients yuri amatnieks aspergillus collection a. glaucus a. flavus a. fumigatus a. nidulans a. niger a. terreus a. sydowii eanofel images editorial board what is aspergillosis search info chronic pulmonary aspergillosis (cpa) and aspergilloma aspergillosis is an infection caused by the fungus aspergillus. aspergillosis describes a large number of diseases involving both infection and growth of fungus as well as allergic responses. aspergillosis can occur in a variety of organs, both in humans and animals. the most common sites of infection are the respiratory apparatus (lungs, sinuses) and these infections can be: invasive (e.g. invasive pulmonary aspergillosis - ipa) non-invasive (e.g. allergic pulmonary aspergillosis - abpa) chronic pulmonary and aspergilloma (e.g chronic cavitary, semi-invasive) severe asthma with fungal sensitisation (safs) chronic pulmonary aspergillosis - cpa is a long-term aspergillus infection of the lung and aspergillus fumigatus is almost always the species responsible for this illness. patients fall into several groups as listed below. those with an aspergilloma which is a ball of fungus found in a single lung cavity - which may improve or disappear, or change very little over a few years. chronic cavitary pulmonary aspergillosis (ccpa) where cavities are present in the lungs, but not necessarily with a fungal ball (aspergilloma). chronic fibrosing pulmonary aspergillosis this may develop where pulmonary aspergillosis remains untreated and chronic scarring of the lungs occurs. unfortunately scarring of the lungs does not improve. most patients with cpa have or have had an underlying lung disease. the most common diseases include tuberculosis, atypical mycobacterium infection, stage iii fibrocystic pulmonary sarcoidosis, abpa, lung cancer, copd and emphysema, asthma and silicosis. diagnosis the specific criteria for diagnosis of cpa are: chest x-rays showing one or more lung cavities. there may be a fungal ball present or not. symptoms lasting more than 3 months, usually including weight loss, fatigue, cough, coughing blood (haemoptysis) and breathlessness a blood test or tissue fluid test positive for aspergillus species aspergilloma an aspergilloma is a fungal mass caused by a fungal infection with aspergillus species that grows in either scarred lungs or in a pre-existing lung cavity, which may have been caused by a previous infection. patients with a previous history of tuberculosis , sarcoidosis , cystic fibrosis or other lung disease are most susceptible to an aspergilloma. aspergillomas may have no specific symptoms but in many patients there is some coughing up of blood called haemoptysis - this may be infrequent and in small quantity, but can be severe and then it requires urgent medical help. tests used to diagnose an aspergilloma may include: chest x-ray chest ct sputum culture bronchoscopy or bronchoscopy with lavage (bal) serum precipitins for aspergillus (blood test to detect antibodies to aspergillus) almost all aspergillomas are caused by aspergillus fumigatus . in diabetic patients it may be caused by aspergillus niger . it is very rarely caused by aspergillus flavus , aspergillus oryzae , aspergillus terreus or aspergillus nidulans . treatment patients with single aspergillomas generally do well with surgery to remove the aspergilloma, and are best given pre-and post-operative antifungal drugs. often, no treatment is necessary. however, if a patient coughs up blood (haemoptysis), treatment may be required (usually angiography and embolisation, surgery or taking tranexamic acid). angiography (injection of dye into the blood vessels) may be used to locate the site of bleeding which may be stopped by shooting tiny pellets into the bleeding vessel. for more complex, chronic cases, lifelong use of antifungal drugs is usual, along with chest x-rays to monitor progress. it is important to monitor the blood levels of antifungals to ensure optimal dosing as individuals vary in their absorption levels of these drugs. note: the text of this page is available for modification and reuse under the terms of the creative commons attribution-sharealike 3.0 unported license and the gnu free documentation license (unversioned, with no invariant sections, front-cover texts, or back-cover texts). about us ¦ privacy policy ¦ terms and condition & copyright policies and our disclaimer ¦ site information ¦ site map ¦ our sponsors ¦ contact us please note: the aspergillus website does not accept advertisments , all content is published on merit bb.com site sponsors this site complies with the honcode standard for trustworthy health information: verify here. search only trustworthy honcode health websites: webness

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https://www.aspergillus.org.uk/content/chronic-pulmonary-aspergillosis-cpa-and-aspergilloma-0/content/educational-materials
https://www.aspergillus.org.uk/content/chronic-pulmonary-aspergillosis-cpa-and-aspergilloma-0/content/antifungal-drug-interactions
https://www.aspergillus.org.uk/content/chronic-pulmonary-aspergillosis-cpa-and-aspergilloma-0/jobs
https://www.aspergillus.org.uk/content/chronic-pulmonary-aspergillosis-cpa-and-aspergilloma-0/laboratory-protocols
http://www.aspergillus.org.uk/content/yuri-amatniek-aspergillus-images
https://www.aspergillus.org.uk/content/chronic-pulmonary-aspergillosis-cpa-and-aspergilloma-0/theses
https://www.aspergillus.org.uk/content/chronic-pulmonary-aspergillosis-cpa-and-aspergilloma-0/fullcalendar
https://www.aspergillus.org.uk/content/chronic-pulmonary-aspergillosis-cpa-and-aspergilloma-0/content/global-aspergillosis-statistics
https://www.aspergillus.org.uk/content/chronic-pulmonary-aspergillosis-cpa-and-aspergilloma-0/content/eanofel-images
https://www.aspergillus.org.uk/content/chronic-pulmonary-aspergillosis-cpa-and-aspergilloma-0/content/england-aspergillosis-primary-diagnosis-1998-2015
https://www.aspergillus.org.uk/content/chronic-pulmonary-aspergillosis-cpa-and-aspergilloma-0/diagnostics
https://www.aspergillus.org.uk/content/chronic-pulmonary-aspergillosis-cpa-and-aspergilloma-0/medical_information
https://www.aspergillus.org.uk/content/chronic-pulmonary-aspergillosis-cpa-and-aspergilloma-0/new-antifungals
https://www.aspergillus.org.uk/content/chronic-pulmonary-aspergillosis-cpa-and-aspergilloma-0/conference-abstracts
https://www.aspergillus.org.uk/content/chronic-pulmonary-aspergillosis-cpa-and-aspergilloma-0/scientific_information
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